The movie begins with Eugene (Zach Cregger) and his best friend Tucker (Trevor Moore (comedian)) as kids. They sneak into the bedroom closet of Eugene's brother, as he recently acquired a valuable Michael Jordan rookie card. Upon opening the box the card was in, Tucker notices that Eugene's brother has an issue of ''Playboy''. Tucker opens the magazine, instantly becoming obsessed with it. Three weeks later, Tucker's demeanor has changed to that of a hormone driven teenager, despite that he is only 8 years old. Fast forward ten years later, Eugene and Tucker are seniors in high school.