When sixteen-year-old Cady Heron moves from Africa to the US, she quickly learns that social life at her new high school is run by queen bee Regina George and her mean girl crew, collectively known as The Plastics. Along with pals Damien and Janice, Cady hatches a plan to take down The Plastics from inside by infiltrating the group — a perfect plan, if only Cady can stay true to herself.