While illegally procuring a brain for his next experiment, Baron Victor Frankenstein is surprised by a thief when he returns to his lab. The Baron destroys most of the evidence and moves on, with a haughty police inspector on his trail. He obtains a room at a boarding house run by Anna, whose fiance Karl is a doctor at the local insane asylum where a former scientific collaborator of the Baron's, who has lost his mind, now resides.