Some years after fighting Monroe "Undisputed" Hutchens in prison, former boxing champion George "Iceman" Chambers visits the Russian Federation for a series of boxing matches, where he is subsequently framed for Possession of drug paraphernalia of cocaine and once again sent to prison. There, he discovers a series of Illegal sports mixed martial arts matches dominated by inmate Yuri Boyka. The prison officials arrange these fights and place large side-bets to make a personal profit, often at the expense of the fighters. Chambers shares a cell with Steven Parker, a British junkie.